You need to edit the registry to allow the windows Installer Service to run under the save mode in order to uninstall applications.
Save mode Registry key:
HKLMSYSTEMCurrentControlSetControlSafeBootMinimal
Right-click on Minimal
and select New -> Key
Name the key MSIService and change the default value to Service by double-clicking it
Networking Safe Mode Registry key:
HKLMSYSTEMCurrentControlSetControlSafeBootNetwork
After boot into the save mode
run the following command:
net start msiserver